- 脆性x智力低下
- 脆性x綜合征
- fragile: adj. 1.脆的，易碎的。 2.脆弱的，虛弱的。 短語 ...
- x: vt. (x-ed, x'd x-ing, x'ing) ...
- mental retardation: 智力缺陷，精神薄弱，智力遲鈍。
- fragile x-associated mental retardation: 脆性x連鎖智力低下
- x-linked mental retardation: x連鎖智力障礙
下載手機(jī)詞典可隨時隨地查詞查翻譯
fragile x mental retardation中文什么意思
- 脆性x智力低下
- 脆性x綜合征
下載手機(jī)詞典可隨時隨地查詞查翻譯
例句與用法
- Fxs is mainly caused by a kind of dynamic mutation , the expansion of a cgg repeat located in the 5 ' - untranslated region ( 5 ' - utr ) of the fmr1 ( fragile x mental retardation ) gene
該綜合癥由患者細(xì)胞中可見xq27 . 3的脆性位點fraxa而得名。絕大多數(shù)脆性x綜合征患者的發(fā)病是由于fmr1基因5端非翻譯區(qū)的三核苷酸cgg重復(fù)的不穩(wěn)定擴(kuò)增所致。 - The absence of the fmr1 gene product , fragile x mental retardation protein ( fmrp ) , is believed to be responsible for the typical physical and mental characteristics of the fragile x syndrome . alleles with between 43 and 200 cgg repeats are called permutation . they are generally unmethylated with normal transcript and protein level , but are extremely unstable during transmission to next generation
帶有前突變( n = 43 200 )的個體其fmr1基因通常不會甲基化，可以正常轉(zhuǎn)錄和翻譯產(chǎn)生fmrp ，故沒有臨床表型出現(xiàn)，但是，在向下一代傳遞的過程中卻是非常不穩(wěn)定的，會從前突變擴(kuò)增成為全突變。